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Wang, Hay-Yan Jack



Wang, Hay-Yan Jack


Associate Professor


lipidomics, metabolomics, bioanalysis method development, biological mass spectrometry application.



886-7-5252000 Ext:3611



  Highest Education: Ph.D., The Johns Hopkins University Bloomberg School of Public Health, U.S.A. (2002)

  Research projects
Lipidomics and metabolomics of inflammatory diseases
3 Drug metabolism and pharmacokinetic (DMPK) studies
4 Bioanalytical method development and proeomic studies



H.Y.J. Wang*, H.W. Wu, P.J. Tsai, C.B. Liu, Zhi-Fu Zheng (2014) Matrix-Assisted Laser Desorption/Ionization Mass Spectrometry Imaging of Cardiolipin in Rat Organ Sections Anal. Bioanal. Chem. 406(2):565-575.


K.C. Wei*, P.C. Chu, H.Y.J. Wang, C.Y. Huang, P.Y. Chen, H.C. Tsai, Y.J. Lu, I.C. Tseng, P.Y. Lee, T.C. Yen, and H.L. Liu* (2013) Focused Ultrasound-induced Blood–Brain Barrier Opening to Enhance Temozolomide Delivery for Glioblastoma Treatment: A Preclinical Study. PLoS ONE 8(3): e58995 .


H.Y.J. Wang*, H.W. Wu, P.J. Tsai, C.B. Liu (2012) MALDI-mass spectrometry imaging of desalted rat brain sections reveals ischemia-mediated changes of lipids. Anal. Bioanal. Chem. 404 (1): 113-124.

4 Y.S. Wang, H.Y.J. Wang, Y.C. Liao, P.C. Tsai, K.C. Chen, H.Y. Cheng, R.T. Lin, S.H. Juo* (2012) MicroRNA-195 regulates vascular smooth muscle cell phenotypes and prevents neointimal formation. Cardiovasc. Res. 95: 517-526.
5 H.Y.J. Wang*, C.B. Liu, H.W. Wu (2011) A simple desalting method for direct MALDI mass spectrometry profiling of tissue lipids. J. Lipid Res. 52(4): 840-849.
6 H.Y.J. Wang*, C.B. Liu, H.W. Wu, and J.S. Kuo (2010) Direct profiling of phospholipids and lysophospholipids in rat brain sections after ischemic stroke. Rapid Commun. Mass Spectrom. 24 (14):2057-2064.
7 H.Y. Wang, L.H. Lo, Y.C. Tyan, H.C. Chen, M.H. Yang, T.Y. Chen, H.Y.J. Wang*, and J. Shiea* (2010) The study of the distribution of melamine in rat renal tissues by imaging mass spectrometry. Anal. Methods 2: 1974-1981.
8 H.Y. J. Wang, S.N. Jackson, J. Post, and A.S. Woods* (2008) A minimalist approach to MALDI imaging of glycerophospholipids and sphingolipids in rat brain tissues. Int. J. Mass Spectrom. 278 (2-3): 143-149.
9 H.Y. J. Wang, S.N. Jackson, and A.S. Woods* (2007) Direct analysis of cardiolipin from rat organ sections. J. Am. Soc. Mass. Spectrom. 18 (3): 567-577.